Cargando…

Cobalt-catalysed C–H carbonylative cyclisation of aliphatic amides

A cobalt-catalysed C–H carbonylation of aliphatic carboxamide derivatives is described, employing commercially available Co(ii)-salts in the presence of a silver oxidant. This operationally simple process utilises an atmospheric pressure of CO and generates a range of substituted succinimide product...

Descripción completa

Detalles Bibliográficos
Autores principales: Williamson, Patrick, Galván, Alicia, Gaunt, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431632/
https://www.ncbi.nlm.nih.gov/pubmed/28553492
http://dx.doi.org/10.1039/c6sc05581h
Descripción
Sumario:A cobalt-catalysed C–H carbonylation of aliphatic carboxamide derivatives is described, employing commercially available Co(ii)-salts in the presence of a silver oxidant. This operationally simple process utilises an atmospheric pressure of CO and generates a range of substituted succinimide products bearing diverse functional groups that can be successfully accessed via this methodology.