Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid

The one-step dehydration, decarboxylation and hydrogenation of the bio-based and widely available citric acid is presented. This reaction sequence yields methylsuccinic acid with yields of up to 89%. Optimal balances between the reaction rates of the different steps were found by varying the hydroge...

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Detalles Bibliográficos
Autores principales: Verduyckt, Jasper, De Vos, Dirk E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431699/
https://www.ncbi.nlm.nih.gov/pubmed/28553496
http://dx.doi.org/10.1039/c6sc04541c
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author Verduyckt, Jasper
De Vos, Dirk E.
author_facet Verduyckt, Jasper
De Vos, Dirk E.
author_sort Verduyckt, Jasper
collection PubMed
description The one-step dehydration, decarboxylation and hydrogenation of the bio-based and widely available citric acid is presented. This reaction sequence yields methylsuccinic acid with yields of up to 89%. Optimal balances between the reaction rates of the different steps were found by varying the hydrogenation catalyst and the reaction parameters (H(2) pressure, pH, temperature, time and catalyst-to-substrate ratio).
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spelling pubmed-54316992017-05-26 Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid Verduyckt, Jasper De Vos, Dirk E. Chem Sci Chemistry The one-step dehydration, decarboxylation and hydrogenation of the bio-based and widely available citric acid is presented. This reaction sequence yields methylsuccinic acid with yields of up to 89%. Optimal balances between the reaction rates of the different steps were found by varying the hydrogenation catalyst and the reaction parameters (H(2) pressure, pH, temperature, time and catalyst-to-substrate ratio). Royal Society of Chemistry 2017-04-01 2017-01-16 /pmc/articles/PMC5431699/ /pubmed/28553496 http://dx.doi.org/10.1039/c6sc04541c Text en This journal is © The Royal Society of Chemistry 2017 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Verduyckt, Jasper
De Vos, Dirk E.
Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
title Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
title_full Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
title_fullStr Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
title_full_unstemmed Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
title_short Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
title_sort highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431699/
https://www.ncbi.nlm.nih.gov/pubmed/28553496
http://dx.doi.org/10.1039/c6sc04541c
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