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Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles

Oleanolic acid (OA), a pentacyclic triterpene, is used to safely and economically treat hepatopathy. However, OA, a Biopharmaceutics Classification System IV category drug, has low bioavailability owing to low solubility (<1 μg/mL) and biomembrane permeability. We developed a novel OA nanoparticl...

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Detalles Bibliográficos
Autores principales:	Xia, Xiaojing, Liu, Haowei, Lv, Huixia, Zhang, Jing, Zhou, Jianping, Zhao, Zhiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431734/ https://www.ncbi.nlm.nih.gov/pubmed/28533680 http://dx.doi.org/10.2147/DDDT.S133997

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