Cargando…

Long non-coding RNA PARTICLE bridges histone and DNA methylation

PARTICLE (Gene PARTICL- ‘Promoter of MAT2A-Antisense RadiaTion Induced Circulating LncRNA) expression is transiently elevated following low dose irradiation typically encountered in the workplace and from natural sources. This long non-coding RNA recruits epigenetic silencers for cis-acting repressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	O’Leary, Valerie Bríd, Hain, Sarah, Maugg, Doris, Smida, Jan, Azimzadeh, Omid, Tapio, Soile, Ovsepian, Saak Victor, Atkinson, Michael John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431818/ https://www.ncbi.nlm.nih.gov/pubmed/28496150 http://dx.doi.org/10.1038/s41598-017-01875-1

Ejemplares similares

PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome
por: O’Leary, Valerie Bríd, et al.
Publicado: (2017)

The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients
por: O'Leary, Valerie Bríd, et al.
Publicado: (2017)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
por: O’Leary, Valerie Bríd, et al.
Publicado: (2020)

The circRNA interactome–innovative hallmarks of the intra- and extracellular radiation response
por: O'Leary, Valerie Bríd, et al.
Publicado: (2017)

Unpacking Pandora from Its Box: Deciphering the Molecular Basis of the SARS-CoV-2 Coronavirus
por: O’Leary, Valerie Bríd, et al.
Publicado: (2020)

Enhanced Extracellular Transfer of HLA-DQ Activates CD3(+) Lymphocytes towards Compromised Treg Induction in Celiac Disease
por: Hudec, Michael, et al.
Publicado: (2022)

The Immunological Epigenetic Landscape of the Human Life Trajectory
por: Juříčková, Iva, et al.
Publicado: (2022)

Ageing perspective on cognitive outcomes from reproductive hormone adjustments
por: Zhang, Grace, et al.
Publicado: (2023)

All-Trans Retinoic Acid Fosters the Multifarious U87MG Cell Line as a Model of Glioblastoma
por: Pokorná, Markéta, et al.
Publicado: (2021)

Integrative multiomics study for validation of mechanisms in radiation-induced ischemic heart disease in Mayak workers
por: Papiez, Anna, et al.
Publicado: (2018)

Molecular Biomarkers of Neuronal Injury in Epilepsy Shared with Neurodegenerative Diseases
por: Negi, Deepika, et al.
Publicado: (2023)

Disruption of Myelin Leads to Ectopic Expression of K(V)1.1 Channels with Abnormal Conductivity of Optic Nerve Axons in a Cuprizone-Induced Model of Demyelination
por: Bagchi, Bandita, et al.
Publicado: (2014)

Data-Independent Acquisition Proteomics Reveals Long-Term Biomarkers in the Serum of C57BL/6J Mice Following Local High-Dose Heart Irradiation
por: Azimzadeh, Omid, et al.
Publicado: (2021)

How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation
por: Poos, Kathrin, et al.
Publicado: (2013)

Radiation Response of Human Cardiac Endothelial Cells Reveals a Central Role of the cGAS-STING Pathway in the Development of Inflammation
por: Philipp, Jos, et al.
Publicado: (2020)

Acute and Chronic Sleep Deprivation-Related Changes in N-methyl-D-aspartate Receptor—Nitric Oxide Signalling in the Rat Cerebral Cortex with Reference to Aging and Brain Lateralization
por: Kristofikova, Zdenka, et al.
Publicado: (2019)

Cholinergic neurons—keeping check on amyloid β in the cerebral cortex
por: Ovsepian, Saak V., et al.
Publicado: (2013)

Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer's Disease
por: Hromadkova, Lenka, et al.
Publicado: (2019)

Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography
por: Olefir, Ivan, et al.
Publicado: (2019)

Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation
por: Poos, Kathrin, et al.
Publicado: (2014)

Genomic Heterogeneity of Osteosarcoma - Shift from Single Candidates to Functional Modules
por: Poos, Kathrin, et al.
Publicado: (2015)

Activation of PPARα by Fenofibrate Attenuates the Effect of Local Heart High Dose Irradiation on the Mouse Cardiac Proteome
por: Azimzadeh, Omid, et al.
Publicado: (2021)

Extended Near-Infrared Optoacoustic Spectrometry for Sensing Physiological Concentrations of Glucose
por: Ghazaryan, Ara, et al.
Publicado: (2018)

Autoantibodies targeting neuronal proteins as biomarkers for neurodegenerative diseases
por: Kocurova, Gabriela, et al.
Publicado: (2022)

Dendritic spine remodeling and plasticity under general anesthesia
por: Granak, Simon, et al.
Publicado: (2021)

In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome
por: Bakshi, Mayur V., et al.
Publicado: (2016)

Endogenous Modulators of NMDA Receptor Control Dendritic Field Expansion of Cortical Neurons
por: Jorratt, Pascal, et al.
Publicado: (2022)

Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE (-/-) Mice
por: Barjaktarovic, Zarko, et al.
Publicado: (2019)

New Small Molecules Targeting Apoptosis and Cell Viability in Osteosarcoma
por: Maugg, Doris, et al.
Publicado: (2015)

Radiation–Induced Signaling Results in Mitochondrial Impairment in Mouse Heart at 4 Weeks after Exposure to X-Rays
por: Barjaktarovic, Zarko, et al.
Publicado: (2011)

The PI3K/Akt/mTOR Pathway Is Implicated in the Premature Senescence of Primary Human Endothelial Cells Exposed to Chronic Radiation
por: Yentrapalli, Ramesh, et al.
Publicado: (2013)

Chronic Occupational Exposure to Ionizing Radiation Induces Alterations in the Structure and Metabolism of the Heart: A Proteomic Analysis of Human Formalin-Fixed Paraffin-Embedded (FFPE) Cardiac Tissue
por: Azimzadeh, Omid, et al.
Publicado: (2020)

Radiation Exposure of Peripheral Mononuclear Blood Cells Alters the Composition and Function of Secreted Extracellular Vesicles
por: Moertl, Simone, et al.
Publicado: (2020)

Neurotoxin-Derived Optical Probes for Biological and Medical Imaging
por: Ergen, Pinar Helin, et al.
Publicado: (2023)

A dose-dependent perturbation in cardiac energy metabolism is linked to radiation-induced ischemic heart disease in Mayak nuclear workers
por: Azimzadeh, Omid, et al.
Publicado: (2016)

Late Effects of Chronic Low Dose Rate Total Body Irradiation on the Heart Proteome of ApoE(−/−) Mice Resemble Premature Cardiac Ageing
por: Azimzadeh, Omid, et al.
Publicado: (2023)

Targets in Epigenetics: Inhibiting the Methyl Writers of the Histone Code
por: Yost, Julianne M, et al.
Publicado: (2011)

Bridging the gaps in Particle Therapy using Monte Carlo Codes
por: Kozlowska, Wioletta
Publicado: (2023)

Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells
por: Mutschelknaus, Lisa, et al.
Publicado: (2017)

Combined Treatment with Low-Dose Ionizing Radiation and Ketamine Induces Adverse Changes in CA1 Neuronal Structure in Male Murine Hippocampi
por: Hladik, Daniela, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lhdr20kuqo89o85cgbu0ee1rbg