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Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection

BACKGROUND: Sun’s procedure is a surgical technique widely used in type A aortic dissection. The purpose of this study was to analyze clinical outcomes and morphologic changes in true and false lumen by computed tomography (CT) angiography after Sun’s procedure. MATERIAL/METHODS: We retrospectively...

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Autores principales: Luo, Jiawen, Fu, Xianming, Zhou, Yangzhao, Tang, Hao, Song, Guobao, Tang, Tao, Liao, Xiaobo, Zhou, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431888/
https://www.ncbi.nlm.nih.gov/pubmed/28475566
http://dx.doi.org/10.12659/MSM.900345
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author Luo, Jiawen
Fu, Xianming
Zhou, Yangzhao
Tang, Hao
Song, Guobao
Tang, Tao
Liao, Xiaobo
Zhou, Xinmin
author_facet Luo, Jiawen
Fu, Xianming
Zhou, Yangzhao
Tang, Hao
Song, Guobao
Tang, Tao
Liao, Xiaobo
Zhou, Xinmin
author_sort Luo, Jiawen
collection PubMed
description BACKGROUND: Sun’s procedure is a surgical technique widely used in type A aortic dissection. The purpose of this study was to analyze clinical outcomes and morphologic changes in true and false lumen by computed tomography (CT) angiography after Sun’s procedure. MATERIAL/METHODS: We retrospectively reviewed 51 patients who underwent Sun’s procedure for acute Stanford type A aortic dissection extending down to iliac bifurcation between January 2013 and December 2014. The images of preoperative, one-month, three-month, and six-month follow-up were analyzed by CT angiography to measure the area and diameter of true and false lumen. RESULTS: Four patients died before surgical intervention and postoperative deaths occurred in five patients (in-hospital mortality rate 10.6%). Only 42 patients (36 male, 6 female; mean age, 45.9±9.8 years; range, 24–65 years) with acute type A aortic dissection were involved in our study. Thirty-five patients (83.3%) suffered from chest or abdominal pain and only one patient (2.4%) was asymptomatic. Thirty-seven patients (88.1%) had hypertension as the most common comorbidity. In the ascending aorta, false lumen was eliminated and the change of true lumen was not significant (p>0.05). In the descending aorta, complete and partial thrombosis of false lumen were observed in eight patients (19.0%) and 33 patients (78.6%) by one-month follow-up CT scan, respectively. After the six-month follow-up, the rate of complete thrombosis increased to 36.1% and partial thrombosis decreased to 61.9%. The area and maximal diameter of true lumen were increased significantly (p<0.05), whereas significant decreases were found in the area and maximal diameter of false lumen (p<0.05). In the abdominal aorta, thrombosis was found in 52.4% patients at one-month follow-up CT. Furthermore, there were no significant changes in both true and false lumen within three months (p>0.05). Nevertheless, the false luminal area and maximal diameter decreased significantly (p<0.05) after six months, while these changes of true lumen were not significant (p>0.05). CONCLUSIONS: After Sun’s procedure, aortic remodeling was a continuous process and occurred in a predictable model, and the extent of aortic remodeling varied at different levels. Remodeling in descending thoracic aorta was earlier than it was in abdominal aorta.
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spelling pubmed-54318882017-05-22 Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection Luo, Jiawen Fu, Xianming Zhou, Yangzhao Tang, Hao Song, Guobao Tang, Tao Liao, Xiaobo Zhou, Xinmin Med Sci Monit Clinical Research BACKGROUND: Sun’s procedure is a surgical technique widely used in type A aortic dissection. The purpose of this study was to analyze clinical outcomes and morphologic changes in true and false lumen by computed tomography (CT) angiography after Sun’s procedure. MATERIAL/METHODS: We retrospectively reviewed 51 patients who underwent Sun’s procedure for acute Stanford type A aortic dissection extending down to iliac bifurcation between January 2013 and December 2014. The images of preoperative, one-month, three-month, and six-month follow-up were analyzed by CT angiography to measure the area and diameter of true and false lumen. RESULTS: Four patients died before surgical intervention and postoperative deaths occurred in five patients (in-hospital mortality rate 10.6%). Only 42 patients (36 male, 6 female; mean age, 45.9±9.8 years; range, 24–65 years) with acute type A aortic dissection were involved in our study. Thirty-five patients (83.3%) suffered from chest or abdominal pain and only one patient (2.4%) was asymptomatic. Thirty-seven patients (88.1%) had hypertension as the most common comorbidity. In the ascending aorta, false lumen was eliminated and the change of true lumen was not significant (p>0.05). In the descending aorta, complete and partial thrombosis of false lumen were observed in eight patients (19.0%) and 33 patients (78.6%) by one-month follow-up CT scan, respectively. After the six-month follow-up, the rate of complete thrombosis increased to 36.1% and partial thrombosis decreased to 61.9%. The area and maximal diameter of true lumen were increased significantly (p<0.05), whereas significant decreases were found in the area and maximal diameter of false lumen (p<0.05). In the abdominal aorta, thrombosis was found in 52.4% patients at one-month follow-up CT. Furthermore, there were no significant changes in both true and false lumen within three months (p>0.05). Nevertheless, the false luminal area and maximal diameter decreased significantly (p<0.05) after six months, while these changes of true lumen were not significant (p>0.05). CONCLUSIONS: After Sun’s procedure, aortic remodeling was a continuous process and occurred in a predictable model, and the extent of aortic remodeling varied at different levels. Remodeling in descending thoracic aorta was earlier than it was in abdominal aorta. International Scientific Literature, Inc. 2017-05-05 /pmc/articles/PMC5431888/ /pubmed/28475566 http://dx.doi.org/10.12659/MSM.900345 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Luo, Jiawen
Fu, Xianming
Zhou, Yangzhao
Tang, Hao
Song, Guobao
Tang, Tao
Liao, Xiaobo
Zhou, Xinmin
Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection
title Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection
title_full Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection
title_fullStr Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection
title_full_unstemmed Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection
title_short Aortic Remodeling Following Sun’s Procedure for Acute Type A Aortic Dissection
title_sort aortic remodeling following sun’s procedure for acute type a aortic dissection
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431888/
https://www.ncbi.nlm.nih.gov/pubmed/28475566
http://dx.doi.org/10.12659/MSM.900345
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