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Stapled BIG3 helical peptide ERAP potentiates anti-tumour activity for breast cancer therapeutics

Estradiol (E2) and the oestrogen receptor-alpha (ERα) signalling pathway play pivotal roles in the proliferative activity of breast cancer cells. Recent findings show that the brefeldin A-inhibited guanine nucleotide-exchange protein 3-prohibitin 2 (BIG3-PHB2) complex plays a crucial role in E2/ERα...

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Detalles Bibliográficos
Autores principales:	Yoshimaru, Tetsuro, Aihara, Keisuke, Komatsu, Masato, Matsushita, Yosuke, Okazaki, Yasumasa, Toyokuni, Shinya, Honda, Junko, Sasa, Mitsunori, Miyoshi, Yasuo, Otaka, Akira, Katagiri, Toyomasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431889/ https://www.ncbi.nlm.nih.gov/pubmed/28500289 http://dx.doi.org/10.1038/s41598-017-01951-6

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