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Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages

Alginate, a natural acidic polysaccharide extracted from marine brown seaweeds, is composed of different blocks of β-(1, 4)-D-mannuronate (M) and its C-5 epimer α-(1, 4)-L-guluronate (G). Alginate-derived guluronate oligosaccharide (GOS) readily activates macrophages. However, to understand its role...

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Detalles Bibliográficos
Autores principales:	Fang, Weishan, Bi, Decheng, Zheng, Ruijin, Cai, Nan, Xu, Hong, Zhou, Rui, Lu, Jun, Wan, Min, Xu, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431981/ https://www.ncbi.nlm.nih.gov/pubmed/28490734 http://dx.doi.org/10.1038/s41598-017-01868-0

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