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Allelic imbalance of somatic mutations in cancer genomes and transcriptomes
Somatic mutations in cancer genomes often show allelic imbalance (AI) of mutation abundance between the genome and transcriptome, but there is not yet a systematic understanding of AI. In this study, we performed large-scale DNA and RNA AI analyses of >100,000 somatic mutations in >2,000 cance...
Autores principales: | Rhee, Je-Keun, Lee, Sejoon, Park, Woong-Yang, Kim, Young-Ho, Kim, Tae-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431982/ https://www.ncbi.nlm.nih.gov/pubmed/28490743 http://dx.doi.org/10.1038/s41598-017-01966-z |
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