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Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress

RNA-binding proteins play a key role in shaping gene expression profiles during stress, however, little is known about the dynamic nature of these interactions and how this influences the kinetics of gene expression. To address this, we developed kinetic cross-linking and analysis of cDNAs (χCRAC),...

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Detalles Bibliográficos
Autores principales: van Nues, Rob, Schweikert, Gabriele, de Leau, Erica, Selega, Alina, Langford, Andrew, Franklin, Ryan, Iosub, Ira, Wadsworth, Peter, Sanguinetti, Guido, Granneman, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432031/
https://www.ncbi.nlm.nih.gov/pubmed/28400552
http://dx.doi.org/10.1038/s41467-017-00025-5