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Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate

The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates. Light sensitivity is restored when apo-opsin com...

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Detalles Bibliográficos
Autores principales: Kaylor, Joanna J., Xu, Tongzhou, Ingram, Norianne T., Tsan, Avian, Hakobyan, Hayk, Fain, Gordon L., Travis, Gabriel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432035/
https://www.ncbi.nlm.nih.gov/pubmed/28473692
http://dx.doi.org/10.1038/s41467-017-00018-4