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Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates. Light sensitivity is restored when apo-opsin com...
Autores principales: | Kaylor, Joanna J., Xu, Tongzhou, Ingram, Norianne T., Tsan, Avian, Hakobyan, Hayk, Fain, Gordon L., Travis, Gabriel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432035/ https://www.ncbi.nlm.nih.gov/pubmed/28473692 http://dx.doi.org/10.1038/s41467-017-00018-4 |
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