Cargando…

Personalized Drug Analysis in B Cell Chronic Lymphocytic Leukemia Patients

BACKGROUND: B cell chronic lymphocytic leukemia (B-CLL) is the most common adult leukemia in the Western world. Although therapeutic advances have notably improved the outcome for many patients, B-CLL remains an incurable disease. The purpose of this study was to search for therapeutic drugs based o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Guozhen, Hu, Xiaoling, Gao, Lei, Feng, Zhenjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432060/ https://www.ncbi.nlm.nih.gov/pubmed/28477439 http://dx.doi.org/10.12659/MSM.900738

Ejemplares similares

Bromodomains and Extra-Terminal (BET) Inhibitor JQ1 Suppresses Proliferation of Acute Lymphocytic Leukemia by Inhibiting c-Myc-Mediated Glycolysis
por: Zhang, Meng-Yi, et al.
Publicado: (2020)

Role of B and T Lymphocyte Attenuator in Renal Transplant Recipients with Biopsy-Proven Acute Rejection
por: Wang, Zijie, et al.
Publicado: (2018)

Inhibition of Siah2 Ubiquitin Ligase by Vitamin K3 Attenuates Chronic Myeloid Leukemia Chemo-Resistance in Hypoxic Microenvironment
por: Huang, Jixian, et al.
Publicado: (2018)

Long Noncoding RNA (lncRNA) Small Nucleolar RNA Host Gene 5 (SNHG5) Regulates Proliferation, Differentiation, and Apoptosis of K562 Cells in Chronic Myeliod Leukemia
por: Gao, Bing, et al.
Publicado: (2019)

A Systems Biology-Based Approach to Uncovering Molecular Mechanisms Underlying Effects of Traditional Chinese Medicine Qingdai in Chronic Myelogenous Leukemia, Involving Integration of Network Pharmacology and Molecular Docking Technology
por: Zhou, Chao, et al.
Publicado: (2018)

Using Prognosis-Related Gene Expression Signature and Connectivity Map for Personalized Drug Repositioning in Multiple Myeloma
por: Zhu, Fang-xiao, et al.
Publicado: (2019)

Low Expression of Pseudogene POU5F1B Affects Diagnosis and Prognosis in Acute Myeloid Leukemia (AML)
por: Yi, Jing, et al.
Publicado: (2019)

Curcumin Alleviates Lipopolysaccharide (LPS)-Activated Neuroinflammation via Modulation of miR-199b-5p/IκB Kinase β (IKKβ)/Nuclear Factor Kappa B (NF-κB) Pathway in Microglia
por: Gao, Feng, et al.
Publicado: (2019)

miR-1260b is a Potential Prognostic Biomarker in Colorectal Cancer
por: Liu, Deng-Rui, et al.
Publicado: (2016)

Potential Molecular Mechanisms and Drugs for Aconitine-Induced Cardiotoxicity in Zebrafish through RNA Sequencing and Bioinformatics Analysis
por: Wang, Mingzhu, et al.
Publicado: (2020)

Identification of Key Genes and Pathways Associated with RUNX1 Mutations in Acute Myeloid Leukemia Using Bioinformatics Analysis
por: Zhu, Fangxiao, et al.
Publicado: (2018)

Effects of Deferoxamine on Leukemia In Vitro and Its Related Mechanism
por: Yang, Yujing, et al.
Publicado: (2018)

Expression and Molecular Regulation of the Cox2 Gene in Gastroenteropancreatic Neuroendocrine Tumors and Antiproliferation of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
por: Gao, Feng, et al.
Publicado: (2018)

Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Ameliorates Cartilage Degradation in a Rat Model of Chronic Sports Arthritic Injury
por: Shang, Lei, et al.
Publicado: (2018)

Micro-RNA-451 Reduces Proliferation of B-CPAP Human Papillary Thyroid Cancer Cells by Downregulating Expression of Activating Transcription Factor 2
por: Zhang, Mei-Feng, et al.
Publicado: (2021)

Impact of Interferon-alpha1b (IFN-α1b) on Antitumor Immune Response: An Interpretation of the Promising Therapeutic Effect of IFN-alpha1b on Melanoma
por: Liu, Yu, et al.
Publicado: (2020)

Hypogelsolinemia in Patients Diagnosed with Acute Myeloid Leukemia at Initial Stage of Sepsis
por: Wątek, Marzena, et al.
Publicado: (2019)

Olmutinib Reverses Doxorubicin Resistance in ETS1-Overexpressing Leukemia Cells
por: Zhong, Jiansheng, et al.
Publicado: (2020)

Emodin, A Chinese Herbal Medicine, Inhibits Reoxygenation-Induced Injury in Cultured Human Aortic Endothelial Cells by Regulating the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Endothelial Nitric Oxide Synthase (eNOS) Signaling Pathway
por: Shou, Xiaoling, et al.
Publicado: (2018)

Upregulation of KIF26B, Cell Migration and Proliferation of Human Ovarian Cancer Cell Lines In Vitro, and Patient Outcomes from Human Bioinformatic Analysis
por: Yang, Xingshuang, et al.
Publicado: (2018)

Jolkinolide A and Jolkinolide B Inhibit Proliferation of A549 Cells and Activity of Human Umbilical Vein Endothelial Cells
por: Shen, Lei, et al.
Publicado: (2017)

The Signal Transducer and Activator of Transcription 5B (STAT5B) Gene Promotes Proliferation and Drug Resistance of Human Mantle Cell Lymphoma Cells by Activating the Akt Signaling Pathway
por: Zhang, Wenjun, et al.
Publicado: (2019)

Baicalin Suppresses Hypoxia-Reoxygenation-Induced Arterial Endothelial Cell Apoptosis via Suppressing PKCδ/p53 Signaling
por: Shou, Xiaoling, et al.
Publicado: (2017)

Role of B-Cell Lymphoma 2 Ovarian Killer (BOK) in Acute Toxicity of Human Lung Epithelial Cells Caused by Cadmium Chloride
por: Zhang, Fang, et al.
Publicado: (2019)

DNA Repair Genes ERCC1 and BRCA1 Expression in Non-Small Cell Lung Cancer Chemotherapy Drug Resistance
por: Wang, Shuai, et al.
Publicado: (2016)

Lysophosphatidic Acid Promotes Expression and Activation of Matrix Metalloproteinase 9 (MMP9) in THP-1 Cells via Toll-Like Receptor 4/Nuclear Factor-κB (TLR4/NF-κB) Signaling Pathway
por: Zhou, Zhi-bin, et al.
Publicado: (2018)

EXT1, Regulated by MiR-665, Promotes Cell Apoptosis via ERK1/2 Signaling Pathway in Acute Lymphoblastic Leukemia
por: Liu, Na-wei, et al.
Publicado: (2019)

Drug Resistance Characteristics and Macrolide-Resistant Mechanisms of Streptococcus pneumoniae in Wenzhou City, China
por: Hu, Dakang, et al.
Publicado: (2016)

Withaferin-A Inhibits Growth of Drug-Resistant Breast Carcinoma by Inducing Apoptosis and Autophagy, Endogenous Reactive Oxygen Species (ROS) Production, and Inhibition of Cell Migration and Nuclear Factor kappa B (Nf-κB)/Mammalian Target of Rapamycin (m-TOR) Signalling Pathway
por: Liu, Xiaokang, et al.
Publicado: (2019)

Knockdown of Long Noncoding RNA POU5F1B Promotes Radiosensitivity in Esophageal Carcinoma
por: Meng, Bi, et al.
Publicado: (2019)

Expression of the miR-148/152 Family in Acute Myeloid Leukemia and its Clinical Significance
por: Wang, Xiao-Xue, et al.
Publicado: (2017)

miR-18a Inhibitor Suppresses Leukemia Cell Proliferation by Upregulation of PTEN Expression
por: Zhang, Liping, et al.
Publicado: (2020)

Weighted Gene Coexpression Network Analysis Identifies Cysteine-Rich Intestinal Protein 1 (CRIP1) as a Prognostic Gene Associated with Relapse in Patients with Acute Myeloid Leukemia
por: Ye, Chengyu, et al.
Publicado: (2019)

Phillygenin Exerts In Vitro and In Vivo Antitumor Effects in Drug-Resistant Human Esophageal Cancer Cells by Inducing Mitochondrial-Mediated Apoptosis, ROS Generation, and Inhibition of the Nuclear Factor kappa B NF-κB Signalling Pathway
por: He, Jiantao, et al.
Publicado: (2019)

Upregulation of MicroRNA-15a Contributes to Pathogenesis of Abdominal Aortic Aneurysm (AAA) by Modulating the Expression of Cyclin-Dependent Kinase Inhibitor 2B (CDKN2B)
por: Gao, Peng, et al.
Publicado: (2017)

Anticancer Effect and Apoptosis Induction of Gambogic Acid in Human Leukemia Cell Line K562 In Vitro
por: Chen, Jinhao, et al.
Publicado: (2015)

Ginsenoside Rg1 Inhibits Cell Proliferation and Induces Markers of Cell Senescence in CD34+CD38− Leukemia Stem Cells Derived from KG1α Acute Myeloid Leukemia Cells by Activating the Sirtuin 1 (SIRT1)/Tuberous Sclerosis Complex 2 (TSC2) Signaling Pathway
por: Tang, Yan-Long, et al.
Publicado: (2020)

Asiaticoside Antagonizes Proliferation and Chemotherapeutic Drug Resistance in Hepatocellular Carcinoma (HCC) Cells
por: Ma, Ying, et al.
Publicado: (2020)

MicroRNA-449b-5p Suppresses Proliferation, Migration, and Invasion of Osteosarcoma by Targeting c-Met
por: Li, Qian, et al.
Publicado: (2019)

Leucine-Rich Alpha-2-Glycoprotein1 Gene Interferes with Regulation of Apoptosis in Leukemia KASUMI-1 Cells
por: Xiao, Shishan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s6klkdohq9d7jfcl0o07kiugji