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Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone
To improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds. Such scaffolds should retain their innate biological and biomechanical capacity and support mesenchymal stem cell (MSC) osteogenic differentiation. However, as allograft bone is de...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432108/ https://www.ncbi.nlm.nih.gov/pubmed/28505164 http://dx.doi.org/10.1371/journal.pone.0177416 |