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Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

To improve the safe use of allograft bone, decellularization techniques may be utilized to produce acellular scaffolds. Such scaffolds should retain their innate biological and biomechanical capacity and support mesenchymal stem cell (MSC) osteogenic differentiation. However, as allograft bone is de...

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Detalles Bibliográficos
Autores principales:	Smith, Christopher A., Board, Tim N., Rooney, Paul, Eagle, Mark J., Richardson, Stephen M., Hoyland, Judith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432108/ https://www.ncbi.nlm.nih.gov/pubmed/28505164 http://dx.doi.org/10.1371/journal.pone.0177416

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