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Whole exome sequencing of a consanguineous family identifies the possible modifying effect of a globally rare AK5 allelic variant in celiac disease development among Saudi patients

Celiac disease (CD), a multi-factorial auto-inflammatory disease of the small intestine, is known to occur in both sporadic and familial forms. Together HLA and Non-HLA genes can explain up to 50% of CD’s heritability. In order to discover the missing heritability due to rare variants, we have exome...

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Detalles Bibliográficos
Autores principales:	Al-Aama, Jumana Yousuf, Shaik, Noor Ahmad, Banaganapalli, Babajan, Salama, Mohammed A., Rashidi, Omran, Sahly, Ahmed N., Mohsen, Mohammed O., Shawoosh, Harbi A., Shalabi, Hebah Ahmad, Edreesi, Mohammad Al, Alharthi, Sameer E., Wang, Jun, Elango, Ramu, Saadah, Omar I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432167/ https://www.ncbi.nlm.nih.gov/pubmed/28505210 http://dx.doi.org/10.1371/journal.pone.0176664

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