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Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target

Adenocarcinoma of the pancreas has a poor prognosis. At present, no relevant personalized targets have been identified. Sequencing studies have implicated gene alterations of disruptor of telomeric silencing 1 like histone lysine methyltransferase (DOT1L) in pancreatic adenocarcinoma. DOT1L is part...

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Detalles Bibliográficos
Autores principales:	Loeser, Heike, Waldschmidt, Dirk, Kuetting, Fabian, Heydt, Carina, Zander, Thomas, Plum, Patrick, Alakus, Hakan, Buettner, Reinhard, Quaas, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432215/ https://www.ncbi.nlm.nih.gov/pubmed/28529740 http://dx.doi.org/10.3892/mco.2017.1194

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