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Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies

Inflammatory breast cancer (IBC) is one of the most lethal breast cancer variants; with existing therapy, 5-yr survival rate is only 35%. Current barriers to successful treatment of IBC include frequent infiltration and the presence of tumor cell clusters, termed tumor emboli, within the breast pare...

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Detalles Bibliográficos
Autores principales:	Arora, Jay, Sauer, Scott J., Tarpley, Michael, Vermeulen, Peter, Rypens, Charlotte, Van Laere, Steven, Williams, Kevin P., Devi, Gayathri R., Dewhirst, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432221/ https://www.ncbi.nlm.nih.gov/pubmed/28460441 http://dx.doi.org/10.18632/oncotarget.15667

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