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Ginsenoside-Rb1 targets chemotherapy-resistant ovarian cancer stem cells via simultaneous inhibition of Wnt/β-catenin signaling and epithelial-to-mesenchymal transition

Chemoresistance is a major clinical problem compromising the successful treatment of cancer. One exciting approach is the eradication of cancer stem/tumor-initiating cells (jointly CSCs), which account for tumor initiation, progression, and drug resistance. Here we show for the first time, with mech...

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Detalles Bibliográficos
Autores principales: Deng, Shan, Wong, Chris Kong Chu, Lai, Hung-Cheng, Wong, Alice Sze Tsai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432225/
https://www.ncbi.nlm.nih.gov/pubmed/27825116
http://dx.doi.org/10.18632/oncotarget.13071

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