C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells

CEBPB copy number gain in Ewing sarcoma was previously shown to be associated with worse clinical outcome compared to tumors with normal CEBPB copy number, although the mechanism was not characterized. We employed gene knockdown and rescue assays to explore the consequences of altered CEBPB gene exp...

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Detalles Bibliográficos
Autores principales: Gardiner, Jamie D., Abegglen, Lisa M., Huang, Xiaomeng, Carter, Bryce E., Schackmann, Elizabeth A., Stucki, Marcus, Paxton, Christian N., Randall, R. Lor, Amatruda, James F., Putnam, Angelica R., Kovar, Heinrich, Lessnick, Stephen L., Schiffman, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432234/
https://www.ncbi.nlm.nih.gov/pubmed/28148901
http://dx.doi.org/10.18632/oncotarget.14847

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