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Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer

Gallbladder cancer (GBC) is a lethal cancer with poor prognosis associated with high invasiveness and poor response to chemotherapy and radiotherapy. New therapeutic approaches are urgently needed in order to improve survival and response rates of GBC patients. We screened 130 small molecule inhibit...

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Detalles Bibliográficos
Autores principales: Weber, Helga, Valbuena, José R., Barbhuiya, Mustafa A., Stein, Stefan, Kunkel, Hana, García, Patricia, Bizama, Carolina, Riquelme, Ismael, Espinoza, Jaime A., Kurtz, Stephen E., Tyner, Jeffrey W., Calderon, Juan Francisco, Corvalán, Alejandro H., Grez, Manuel, Pandey, Akhilesh, Leal-Rojas, Pamela, Roa, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432248/
https://www.ncbi.nlm.nih.gov/pubmed/28412732
http://dx.doi.org/10.18632/oncotarget.15410

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