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Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer
Gallbladder cancer (GBC) is a lethal cancer with poor prognosis associated with high invasiveness and poor response to chemotherapy and radiotherapy. New therapeutic approaches are urgently needed in order to improve survival and response rates of GBC patients. We screened 130 small molecule inhibit...
Autores principales: | Weber, Helga, Valbuena, José R., Barbhuiya, Mustafa A., Stein, Stefan, Kunkel, Hana, García, Patricia, Bizama, Carolina, Riquelme, Ismael, Espinoza, Jaime A., Kurtz, Stephen E., Tyner, Jeffrey W., Calderon, Juan Francisco, Corvalán, Alejandro H., Grez, Manuel, Pandey, Akhilesh, Leal-Rojas, Pamela, Roa, Juan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432248/ https://www.ncbi.nlm.nih.gov/pubmed/28412732 http://dx.doi.org/10.18632/oncotarget.15410 |
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