Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer

Cancer associated fibroblasts (CAFs) are a crucial cellular component in tumor microenvironment and could promote tumor progression. CAFs are usually derived from resident fibroblasts, which undergoing an activated process stimulated by tumor cells. However, the agents and mechanism driving this swi...

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Detalles Bibliográficos
Autores principales: Wang, Linlin, Yang, Dong, Tian, Jing, Gao, Aiqin, Shen, Yihang, Ren, Xia, Li, Xia, Jiang, Guosheng, Dong, Taotao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432260/
https://www.ncbi.nlm.nih.gov/pubmed/28412748
http://dx.doi.org/10.18632/oncotarget.15461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432260/
https://www.ncbi.nlm.nih.gov/pubmed/28412748
http://dx.doi.org/10.18632/oncotarget.15461

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