microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation

Forced-activation of AMP-activated protein kinase (AMPK) can possibly inhibit osteoblastoma cells. Here, we aim to provoke AMPK activation via microRNA silencing its phosphatase Ppm1e (protein phosphatase Mg(2+)/Mn(2+)-dependent 1e). We showed that microRNA-135b-5p (“miR-135b-5p”), the anti-Ppm1e mi...

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Detalles Bibliográficos
Autores principales: Li, Zheng-Wei, Zhu, Yun-Rong, Zhou, Xiao-Zhong, Zhuo, Bao-Biao, Wang, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432269/
https://www.ncbi.nlm.nih.gov/pubmed/28460435
http://dx.doi.org/10.18632/oncotarget.15477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432269/
https://www.ncbi.nlm.nih.gov/pubmed/28460435
http://dx.doi.org/10.18632/oncotarget.15477

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