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microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation
Forced-activation of AMP-activated protein kinase (AMPK) can possibly inhibit osteoblastoma cells. Here, we aim to provoke AMPK activation via microRNA silencing its phosphatase Ppm1e (protein phosphatase Mg(2+)/Mn(2+)-dependent 1e). We showed that microRNA-135b-5p (“miR-135b-5p”), the anti-Ppm1e mi...
Autores principales: | Li, Zheng-Wei, Zhu, Yun-Rong, Zhou, Xiao-Zhong, Zhuo, Bao-Biao, Wang, Xiao-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432269/ https://www.ncbi.nlm.nih.gov/pubmed/28460435 http://dx.doi.org/10.18632/oncotarget.15477 |
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