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Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface
Trichosanthin is a plant toxin belonging to the family of ribosome-inactivating proteins. It has various biological and pharmacological activities, including anti-tumor and immunoregulatory effects. In this study, we explored the potential medicinal applications of trichosanthin in cancer immunother...
Autores principales: | Li, Chunman, Zeng, Meiqi, Chi, Huju, Shen, Jing, Ng, Tzi-Bun, Jin, Guangyi, Lu, Desheng, Fan, Xinmin, Xiong, Bilian, Xiao, Zhangang, Sha, Ou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432272/ https://www.ncbi.nlm.nih.gov/pubmed/28460437 http://dx.doi.org/10.18632/oncotarget.15518 |
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