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Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H(4) receptor agonists and opportunity for combination with radiation
The aims of the work were to improve our knowledge of the role of H(4)R in melanoma proliferation and assess in vivo the therapeutic efficacy of histamine, clozapine and JNJ28610244, an H(4)R agonist, in a preclinical metastatic model of melanoma. Additionally, we aimed to investigate the combinator...
Autores principales: | Massari, Noelia A., Nicoud, Melisa B., Sambuco, Lorena, Cricco, Graciela P., Lamas, Diego J. Martinel, Ducloux, María V. Herrero, Blanco, Horacio, Rivera, Elena S., Medina, Vanina A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432273/ https://www.ncbi.nlm.nih.gov/pubmed/28460440 http://dx.doi.org/10.18632/oncotarget.15594 |
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