Cargando…

The cell polarity protein Scrib functions as a tumor suppressor in liver cancer

Scrib is a membrane protein that is involved in the maintenance of apical-basal cell polarity of the epithelial tissues. However, Scrib has also been shown to be mislocalized to the cytoplasm in breast and prostate cancer. Here, for the first time, we report that Scrib not only translocates to the c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kapil, Shweta, Sharma, Bal Krishan, Patil, Mallikarjun, Elattar, Sawsan, Yuan, Jinling, Hou, Steven X., Kolhe, Ravindra, Satyanarayana, Ande
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432276/ https://www.ncbi.nlm.nih.gov/pubmed/28460446 http://dx.doi.org/10.18632/oncotarget.15713

Ejemplares similares

Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning
por: Patil, Mallikarjun, et al.
Publicado: (2017)

Mutations in Planar Cell Polarity Gene SCRIB Are Associated with Spina Bifida
por: Lei, Yunping, et al.
Publicado: (2013)

An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity
por: Almeida, Stephanie M., et al.
Publicado: (2023)

The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus
por: Petit, Marleen MR, et al.
Publicado: (2005)

Identification and preliminary study of a novel interacting protein SCRIB with fibroblast activation protein in OSCC: SCRIB interacts with fibroblast activation protein in OSCC
por: Liu, Shuyan, et al.
Publicado: (2023)

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis
por: Pearson, Helen B., et al.
Publicado: (2015)

Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium
por: Boczonadi, Veronika, et al.
Publicado: (2014)

Expression and role of hScrib in endometrium, endometriosis, and endometrial adenocarcinoma
por: Ouyang, Zhuo, et al.
Publicado: (2019)

Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer
por: Saito, Yasuhiro, et al.
Publicado: (2022)

Neuron-Specific Deletion of Scrib in Mice Leads to Neuroanatomical and Locomotor Deficits
por: Ezan, Jerome, et al.
Publicado: (2022)

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression
por: Anastas, J N, et al.
Publicado: (2012)

SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer
por: Shen, Hengyang, et al.
Publicado: (2021)

Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms
por: Schimizzi, Gregory V., et al.
Publicado: (2016)

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis
por: Li, Qi, et al.
Publicado: (2009)

Molecular Expression of the Scribble Complex Genes, Dlg, Scrib and Lgl, in Silkworm, Bombyx mori
por: Qi, Hai-Sheng, et al.
Publicado: (2013)

FAM83H and SCRIB stabilize β-catenin and stimulate progression of gastric carcinoma
por: Hussein, Usama Khamis, et al.
Publicado: (2020)

Genetic polymorphism in CD14 gene, a co-receptor of TLR4 associated with non-alcoholic fatty liver disease
por: Kapil, Shweta, et al.
Publicado: (2016)

Differential Regulation of Cell-Cell Contact, Invasion and Anoikis by hScrib and hDlg in Keratinocytes
por: Massimi, Paola, et al.
Publicado: (2012)

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib
por: Sun, Tianliang, et al.
Publicado: (2017)

Ras(V12); scrib(−/−) Tumors: A Cooperative Oncogenesis Model Fueled by Tumor/Host Interactions
por: Dillard, Caroline, et al.
Publicado: (2021)

Differential regulation of Dlg1, Scrib, and Lgl1 expression in a transgenic mouse model of ocular cancer
por: Vieira, V., et al.
Publicado: (2008)

Decreased Usage of Specific Scrib Exons Defines a More Malignant Phenotype of Breast Cancer With Worsened Survival
por: Metodieva, Gergana, et al.
Publicado: (2016)

Individual and Co-Expression Patterns of FAM83H and SCRIB at Diagnosis Are Associated with the Survival of Colorectal Carcinoma Patients
por: Jeong, Tae Young, et al.
Publicado: (2022)

The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib
por: Messa, Lorenzo, et al.
Publicado: (2021)

A dual role of Cdk2 in DNA damage response
por: Satyanarayana, Ande, et al.
Publicado: (2009)

Molecular Signaling Pathways and Therapeutic Targets in Hepatocellular Carcinoma
por: Dimri, Manali, et al.
Publicado: (2020)

The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling
por: Lopez Almeida, Leonor, et al.
Publicado: (2018)

SCRIB Is Involved in the Progression of Ovarian Carcinomas in Association with the Factors Linked to Epithelial-to-Mesenchymal Transition and Predicts Shorter Survival of Diagnosed Patients
por: Hussein, Usama Khamis, et al.
Publicado: (2021)

A Novel Interaction between hScrib and PP1γ Downregulates ERK Signaling and Suppresses Oncogene-Induced Cell Transformation
por: Nagasaka, Kazunori, et al.
Publicado: (2013)

Human DLG1 and SCRIB Are Distinctly Regulated Independently of HPV-16 during the Progression of Oropharyngeal Squamous Cell Carcinomas: A Preliminary Analysis
por: Lulić, Lucija, et al.
Publicado: (2021)

MiR-9-5p Inhibits the MMP(+)-Induced Neuron Apoptosis through Regulating SCRIB/β-Catenin Signaling in Parkinson's Disease
por: Xiao, Zhenyong, et al.
Publicado: (2022)

Macrophages: Their role, activation and polarization in pulmonary diseases
por: Arora, Shweta, et al.
Publicado: (2018)

The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines
por: Kranjec, Christian, et al.
Publicado: (2016)

Genes Regulating Epithelial Polarity Are Critical Suppressors of Esophageal Oncogenesis
por: Li, Xiu-Min, et al.
Publicado: (2015)

Regulation of cell polarity determinants by the Retinoblastoma tumor suppressor protein
por: Payankaulam, Sandhya, et al.
Publicado: (2016)

The Deleted in Liver Cancer 1 (Dlc1) tumor suppressor is haploinsufficient for mammary gland development and epithelial cell polarity
por: Basak, Pratima, et al.
Publicado: (2015)

MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function
por: Yan, Wei, et al.
Publicado: (2021)

Milky urine: A real cause of concern
por: Dhansura, Tasneem S, et al.
Publicado: (2013)

Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble
por: Zeitler, Jennifer, et al.
Publicado: (2004)

Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade
por: Ouzounova, Maria, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_h2qfam88dr5kae2uoecmh11tdm