Cargando…
PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux
Members of the tumor necrosis factor (TNF) transmembrane cytokine superfamily, such as TNFα and Fas ligand (FasL), play crucial roles in inflammation and immunity. TRAIL is a member of this superfamily with the ability to selectively trigger cancer cell death but does not motive cytotoxicity to most...
Autores principales: | Nazim, Uddin MD., Moon, Ji-Hong, Lee, You-Jin, Seol, Jae-Won, Park, Sang-Youel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432299/ https://www.ncbi.nlm.nih.gov/pubmed/28460464 http://dx.doi.org/10.18632/oncotarget.15819 |
Ejemplares similares
-
Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL- induced apoptosis
por: Nazim, Uddin MD, et al.
Publicado: (2016) -
Glipizide sensitizes lung cancer cells to TRAIL-induced apoptosis via Akt/mTOR/autophagy pathways
por: Nazim, Uddin MD., et al.
Publicado: (2017) -
Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein
por: Nazim, Uddin MD., et al.
Publicado: (2017) -
Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS
por: Nazim, Uddin MD., et al.
Publicado: (2019) -
The antidiabetic drug troglitazone protects against PrP (106–126)-induced neurotoxicity via the PPARγ-autophagy pathway in neuronal cells
por: Moon, Ji-Hong, et al.
Publicado: (2021)