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Fungal lectin MpL enables entry of protein drugs into cancer cells and their subcellular targeting

Lectins have been recognized as promising carrier molecules for targeted drug delivery. They specifically bind carbohydrate moieties on cell membranes and trigger cell internalization. Fungal lectin MpL (Macrolepiota procera lectin) does not provoke cancer cell cytotoxicity but is able to bind amino...

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Detalles Bibliográficos
Autores principales: Žurga, Simon, Nanut, Milica Perišić, Kos, Janko, Sabotič, Jerica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432305/
https://www.ncbi.nlm.nih.gov/pubmed/28460472
http://dx.doi.org/10.18632/oncotarget.15849

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