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Human α-L-fucosidase-1 attenuates the invasive properties of thyroid cancer
Glycans containing α-L-fucose participate in diverse interactions between cells and extracellular matrix. High glycan expression on cell surface is often associated with neoplastic progression. The lysosomal exoenzyme, α-L-fucosidase-1 (FUCA-1) removes fucose residues from glycans. The FUCA-1 gene i...
Autores principales: | Vecchio, Giancarlo, Parascandolo, Alessia, Allocca, Chiara, Ugolini, Clara, Basolo, Fulvio, Moracci, Marco, Strazzulli, Andrea, Cobucci-Ponzano, Beatrice, Laukkanen, Mikko O., Castellone, Maria Domenica, Tsuchida, Nobuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432319/ https://www.ncbi.nlm.nih.gov/pubmed/28404918 http://dx.doi.org/10.18632/oncotarget.15635 |
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