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Human α-L-fucosidase-1 attenuates the invasive properties of thyroid cancer

Glycans containing α-L-fucose participate in diverse interactions between cells and extracellular matrix. High glycan expression on cell surface is often associated with neoplastic progression. The lysosomal exoenzyme, α-L-fucosidase-1 (FUCA-1) removes fucose residues from glycans. The FUCA-1 gene i...

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Detalles Bibliográficos
Autores principales: Vecchio, Giancarlo, Parascandolo, Alessia, Allocca, Chiara, Ugolini, Clara, Basolo, Fulvio, Moracci, Marco, Strazzulli, Andrea, Cobucci-Ponzano, Beatrice, Laukkanen, Mikko O., Castellone, Maria Domenica, Tsuchida, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432319/
https://www.ncbi.nlm.nih.gov/pubmed/28404918
http://dx.doi.org/10.18632/oncotarget.15635

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