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Gambogic acid suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition
The epithelial-to-mesenchymal transition (EMT) contributes to the disruption of cell–cell junctions and imbues cancer cells with invasive and migratory properties. In this study, we investigated the effect of gambogic acid, a xanthone extracted from the resin of Garciania hanburyi, on transforming g...
Autores principales: | Zhao, Kai, Zhang, Shuai, Song, Xiuming, Yao, Yuyuan, Zhou, Yuxin, You, Qidong, Guo, Qinglong, Lu, Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432322/ https://www.ncbi.nlm.nih.gov/pubmed/28404892 http://dx.doi.org/10.18632/oncotarget.15449 |
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