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A bispecific enediyne-energized fusion protein targeting both epidermal growth factor receptor and insulin-like growth factor 1 receptor showing enhanced antitumor efficacy against non-small cell lung cancer

Epidermal growth factor receptor (EGFR) and insulin-like growth factor 1 receptor (IGF-1R) both overexpressed on non-small cell lung cancer (NSCLC) and are known cooperatively to promote tumor progression and drug resistance. This study was to construct a novel bispecific fusion protein EGF-IGF-LDP-...

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Detalles Bibliográficos
Autores principales:	Guo, Xiao-Fang, Zhu, Xiao-Fei, Cao, Hai-Ying, Zhong, Gen-Shen, Li, Liang, Deng, Bao-Guo, Chen, Ping, Wang, Pei-Zhen, Miao, Qing-Fang, Zhen, Yong-Su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432335/ https://www.ncbi.nlm.nih.gov/pubmed/28460483 http://dx.doi.org/10.18632/oncotarget.15933

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