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The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner

Pediatric high-grade gliomas (pedHGG) belong to the most aggressive cancers in children with a poor prognosis due to a lack of efficient therapeutic strategies. The β-catenin/Wnt-signaling pathway was shown to hold promising potential as a treatment target in adult high-grade gliomas by abrogating t...

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Detalles Bibliográficos
Autores principales:	Wiese, Maria, Walther, Neele, Diederichs, Christopher, Schill, Fabian, Monecke, Sebastian, Salinas, Gabriela, Sturm, Dominik, Pfister, Stefan M., Dressel, Ralf, Johnsen, Steven A., Kramm, Christof M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432336/ https://www.ncbi.nlm.nih.gov/pubmed/28460484 http://dx.doi.org/10.18632/oncotarget.15934

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