Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer

Advanced ovarian cancer is an incurable disease. Thus, novel therapies are required. We wished to identify new therapeutic targets for ovarian cancer. ShRNA screen performed in 42 ovarian cancer cell lines identified the centriolar replication factor STIL as an essential gene for ovarian cancer cell...

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Detalles Bibliográficos
Autores principales: Rabinowicz, Noa, Mangala, Lingegowda S., Brown, Kevin R., Checa-Rodriguez, Cintia, Castiel, Asher, Moskovich, Oren, Zarfati, Giulia, Trakhtenbrot, Luba, Levy-Barda, Adva, Jiang, Dahai, Rodriguez-Aguayo, Cristian, Pradeep, Sunila, van Praag, Yael, Lopez-Berestein, Gabriel, David, Ahuvit, Novikov, Ilya, Huertas, Pablo, Rottapel, Robert, Sood, Anil K., Izraeli, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432342/
https://www.ncbi.nlm.nih.gov/pubmed/28423708
http://dx.doi.org/10.18632/oncotarget.16068

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