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Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells

The uncontrolled growth of tumor can lead to the formation of area deprived in nutrients. Due to their high genetic instability, tumor cells can adapt and develop resistance to this pro-apoptotic environment. Among the resistance mechanisms, those involved in the resistance to long-term amino acid r...

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Detalles Bibliográficos
Autores principales: Mesclon, Florent, Lambert-Langlais, Sarah, Carraro, Valérie, Parry, Laurent, Hainault, Isabelle, Jousse, Céline, Maurin, Anne-Catherine, Bruhat, Alain, Fafournoux, Pierre, Averous, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432347/
https://www.ncbi.nlm.nih.gov/pubmed/28460466
http://dx.doi.org/10.18632/oncotarget.15828