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Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice

Non-alcoholic fatty liver disease (NAFLD) incorporates steatosis, non-alcoholic steato-hepatitis (NASH) and liver cirrhosis, associating with diabetes and cardiovascular disease (CVD). TNF-related apoptosis-inducing ligand (TRAIL) is protective of CVD. We aimed to determine whether TRAIL protects ag...

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Detalles Bibliográficos
Autores principales: Cartland, Siân P., Harith, Hanis H., Genner, Scott W., Dang, Lei, Cogger, Victoria C., Vellozzi, Melissa, Di Bartolo, Belinda A., Thomas, Shane R., Adams, Leon A., Kavurma, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432513/
https://www.ncbi.nlm.nih.gov/pubmed/28507343
http://dx.doi.org/10.1038/s41598-017-01721-4