Increased leukotoxin production: Characterization of 100 base pairs within the 530 base pair leukotoxin promoter region of Aggregatibacter actinomycetemcomitans

Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virulence factor that kills leukocytes permitting it’s escape from host immune surveillance. A. actinomycetemcomitans strains can produce high or low levels of toxin. Genetic differences reside in the “so called JP2” ltxA promoter re...

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Detalles Bibliográficos
Autores principales: Sampathkumar, Vandana, Velusamy, Senthil Kumar, Godboley, Dipti, Fine, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432517/
https://www.ncbi.nlm.nih.gov/pubmed/28507341
http://dx.doi.org/10.1038/s41598-017-01692-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432517/
https://www.ncbi.nlm.nih.gov/pubmed/28507341
http://dx.doi.org/10.1038/s41598-017-01692-6

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