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GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases

BACKGROUND: Genome editing technologies developed around the CRISPR-Cas9 nuclease system have facilitated the investigation of a broad range of biological questions. These nucleases also hold tremendous promise for treating a variety of genetic disorders. In the context of their therapeutic applicat...

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Detalles Bibliográficos
Autores principales:	Zhu, Lihua Julie, Lawrence, Michael, Gupta, Ankit, Pagès, Hervé, Kucukural, Alper, Garber, Manuel, Wolfe, Scot A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Software
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433024/ https://www.ncbi.nlm.nih.gov/pubmed/28506212 http://dx.doi.org/10.1186/s12864-017-3746-y

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