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Complexity and algorithms for copy-number evolution problems

BACKGROUND: Cancer is an evolutionary process characterized by the accumulation of somatic mutations in a population of cells that form a tumor. One frequent type of mutations is copy number aberrations, which alter the number of copies of genomic regions. The number of copies of each position along...

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Detalles Bibliográficos
Autores principales: El-Kebir, Mohammed, Raphael, Benjamin J., Shamir, Ron, Sharan, Roded, Zaccaria, Simone, Zehavi, Meirav, Zeira, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433102/
https://www.ncbi.nlm.nih.gov/pubmed/28515774
http://dx.doi.org/10.1186/s13015-017-0103-2