Synthesis of D-manno-heptulose via a cascade aldol/hemiketalization reaction

A [4 + 3] synthesis of D-manno-heptulose is described. The cascade aldol/hemiketalization reaction of a C(4) aldehyde with a C(3) ketone provides the differentially protected ketoheptose building block, which can be further reacted to furnish target D-manno-heptulose.

Detalles Bibliográficos
Autores principales: Chen, Yan, Wang, Xiaoman, Wang, Junchang, Yang, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433184/
https://www.ncbi.nlm.nih.gov/pubmed/28546836
http://dx.doi.org/10.3762/bjoc.13.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433184/
https://www.ncbi.nlm.nih.gov/pubmed/28546836
http://dx.doi.org/10.3762/bjoc.13.79

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