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Personalized activity index, a new safety monitoring tool for multiple sclerosis clinical trials
BACKGROUND: An abnormal increase of contrast-enhancing lesion (CEL) counts on frequent MRIs is interpreted as a signal of potential worsening in multiple sclerosis (MS) clinical trials. We demonstrate the utility of the MR personalized activity index (MR-pax) to identify such increases. METHODS: We...
Autores principales: | Zhao, Yinshan, Kondo, Yumi, Traboulsee, Anthony, Li, David KB, Riddehough, Andrew, Petkau, A John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433340/ https://www.ncbi.nlm.nih.gov/pubmed/28607690 http://dx.doi.org/10.1177/2055217315577829 |
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