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Sibling method increases risk assessment estimates for type 1 diabetes

We presented a risk assessment model to distinguish between type 1 diabetes (T1D) affected and unaffected siblings using only three single nucleotide polymorphism (SNP) genotypes. In addition we calculated the heritability from genome-wide identity-by-descent (IBD) sharing between full siblings. We...

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Detalles Bibliográficos
Autores principales:	Lam, Hoang V., Nguyen, Dat T., Nguyen, Cao D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433695/ https://www.ncbi.nlm.nih.gov/pubmed/28510587 http://dx.doi.org/10.1371/journal.pone.0176341

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