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Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase

Movement of the transcription machinery along a template alters DNA topology resulting in the accumulation of supercoils in DNA. The positive supercoils generated ahead of transcribing RNA polymerase (RNAP) and the negative supercoils accumulating behind impose severe topological constraints impedin...

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Detalles Bibliográficos
Autores principales:	Ahmed, Wareed, Sala, Claudia, Hegde, Shubhada R., Jha, Rajiv Kumar, Cole, Stewart T., Nagaraja, Valakunja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433769/ https://www.ncbi.nlm.nih.gov/pubmed/28463980 http://dx.doi.org/10.1371/journal.pgen.1006754

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