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Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice
A novel, selective and sensitive single-ion monitoring (SIM) gas chromatography-mass spectrometry (GCMS) method was developed and validated for the determination of energy metabolites related to glycolysis, the tricarboxylic acid (TCA) cycle, glutaminolysis, and fatty acid β-oxidation. This assay us...
Autores principales: | Patel, Daxesh P., Krausz, Kristopher W., Xie, Cen, Beyoğlu, Diren, Gonzalez, Frank J., Idle, Jeffrey R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433781/ https://www.ncbi.nlm.nih.gov/pubmed/28520815 http://dx.doi.org/10.1371/journal.pone.0177953 |
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