Cargando…

Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity

The recent global challenges to prevent and treat fungal infections strongly demand for the development of new antifungal strategies. The structurally very similar cysteine-rich antifungal proteins from ascomycetes provide a feasible basis for designing new antifungal molecules. The main structural...

Descripción completa

Detalles Bibliográficos
Autores principales:	Galgóczy, László, Borics, Attila, Virágh, Máté, Ficze, Hargita, Váradi, Györgyi, Kele, Zoltán, Marx, Florentine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434006/ https://www.ncbi.nlm.nih.gov/pubmed/28512317 http://dx.doi.org/10.1038/s41598-017-02234-w

Ejemplares similares

Anti-Candidal Activity and Functional Mapping of Recombinant and Synthetic Neosartorya fischeri Antifungal Protein 2 (NFAP2)
por: Tóth, Liliána, et al.
Publicado: (2018)

Biofungicidal Potential of Neosartorya (Aspergillus) Fischeri Antifungal Protein NFAP and Novel Synthetic γ-Core Peptides
por: Tóth, Liliána, et al.
Publicado: (2020)

NFAP2, a novel cysteine-rich anti-yeast protein from Neosartorya fischeri NRRL 181: isolation and characterization
por: Tóth, Liliána, et al.
Publicado: (2016)

Insight into the antifungal mechanism of Neosartorya fischeri antifungal protein
por: Virágh, Máté, et al.
Publicado: (2015)

Hard nut to crack: Solving the disulfide linkage pattern of the Neosartorya (Aspergillus) fischeri antifungal protein 2
por: Váradi, Györgyi, et al.
Publicado: (2023)

The Neosartorya fischeri Antifungal Protein 2 (NFAP2): A New Potential Weapon against Multidrug-Resistant Candida auris Biofilms
por: Kovács, Renátó, et al.
Publicado: (2021)

The combination of Neosartorya (Aspergillus) fischeri antifungal proteins with rationally designed γ-core peptide derivatives is effective for plant and crop protection
por: Tóth, Liliána, et al.
Publicado: (2022)

Confirmation of the Disulfide Connectivity and Strategies for Chemical Synthesis of the Four-Disulfide-Bond-Stabilized Aspergillus giganteus Antifungal Protein, AFP
por: Váradi, Györgyi, et al.
Publicado: (2023)

The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF
por: Sonderegger, Christoph, et al.
Publicado: (2018)

Solution Structure, Dynamics, and New Antifungal Aspects of the Cysteine-Rich Miniprotein PAFC
por: Czajlik, András, et al.
Publicado: (2021)

The potential use of the Penicillium chrysogenum antifungal protein PAF, the designed variant PAF(opt) and its γ‐core peptide Pγ(opt) in plant protection
por: Tóth, Liliána, et al.
Publicado: (2020)

Do Antimicrobial Proteins Contribute to Overcoming the Hidden Antifungal Crisis at the Dawn of a Post-Antibiotic Era?
por: Galgóczy, László, et al.
Publicado: (2019)

Mapping and Identification of Antifungal Peptides in the Putative Antifungal Protein AfpB from the Filamentous Fungus Penicillium digitatum
por: Garrigues, Sandra, et al.
Publicado: (2017)

Cysteine‐Rich Antifungal Proteins from Filamentous Fungi are Promising Bioactive Natural Compounds in Anti‐Candida Therapy
por: Galgóczy, László, et al.
Publicado: (2019)

A Penicillium chrysogenum-based expression system for the production of small, cysteine-rich antifungal proteins for structural and functional analyses
por: Sonderegger, Christoph, et al.
Publicado: (2016)

First evidence of mineralization of petroleum asphaltenes by a strain of Neosartorya fischeri
por: Uribe‐Alvarez, Cristina, et al.
Publicado: (2011)

Small, Cationic Antifungal Proteins from Filamentous Fungi Inhibit Candida albicans Growth in 3D Skin Infection Models
por: Holzknecht, Jeanett, et al.
Publicado: (2022)

Functionality and prevalence of trehalose-based oligosaccharides as novel compatible solutes in ascospores of Neosartorya fischeri (Aspergillus fischeri) and other fungi
por: Wyatt, Timon T, et al.
Publicado: (2015)

Studies on the Chemical Diversities of Secondary Metabolites Produced by Neosartorya fischeri via the OSMAC Method
por: Ying, You-Min, et al.
Publicado: (2018)

Efficient production and characterization of the novel and highly active antifungal protein AfpB from Penicillium digitatum
por: Garrigues, Sandra, et al.
Publicado: (2017)

Potential of Antifungal Proteins (AFPs) to Control Penicillium Postharvest Fruit Decay
por: Gandía, Mónica, et al.
Publicado: (2021)

Microarray analysis of Neosartorya fischeri using different carbon sources, petroleum asphaltenes and glucose-peptone
por: Hernández-López, Edna L., et al.
Publicado: (2015)

Antifungal proteins: More than antimicrobials?
por: Hegedüs, Nikoletta, et al.
Publicado: (2013)

The Penicillium chrysogenum Q176 Antimicrobial Protein PAFC Effectively Inhibits the Growth of the Opportunistic Human Pathogen Candida albicans
por: Holzknecht, Jeanett, et al.
Publicado: (2020)

Structure and Synthesis of Antifungal Disulfide β-Strand Proteins from Filamentous Fungi
por: Váradi, Györgyi, et al.
Publicado: (2018)

Rationally Designed Antimicrobial Peptides Are Potential Tools to Combat Devastating Bacteria and Fungi
por: Váradi, Györgyi, et al.
Publicado: (2022)

Three Antifungal Proteins From Penicillium expansum: Different Patterns of Production and Antifungal Activity
por: Garrigues, Sandra, et al.
Publicado: (2018)

The Membrane Activity of the Amphibian Temporin B Peptide Analog TB_KKG6K Sheds Light on the Mechanism That Kills Candida albicans
por: Kakar, Anant, et al.
Publicado: (2022)

Synthesis of isobemisiose, neosartose, and fischerose: three α-1,6-linked trehalose-based oligosaccharides identified from Neosartorya fischeri
por: Kuenstner, E. J., et al.
Publicado: (2020)

Nutrient Excess Triggers the Expression of the Penicillium chrysogenum Antifungal Protein PAFB
por: Huber, Anna, et al.
Publicado: (2019)

Comparison of Chemical Sensitivity of Fresh and Long-Stored Heat Resistant Neosartorya fischeri Environmental Isolates Using BIOLOG Phenotype MicroArray System
por: Panek, Jacek, et al.
Publicado: (2016)

Two small, cysteine-rich and cationic antifungal proteins from Penicillium chrysogenum: A comparative study of PAF and PAFB
por: Huber, A., et al.
Publicado: (2020)

“Invisible” Conformers of an Antifungal Disulfide Protein Revealed by Constrained Cold and Heat Unfolding, CEST-NMR Experiments, and Molecular Dynamics Calculations
por: Fizil, Ádám, et al.
Publicado: (2015)

Molecular Characterization of a Highly-Active Thermophilic β-Glucosidase from Neosartorya fischeri P1 and Its Application in the Hydrolysis of Soybean Isoflavone Glycosides
por: Yang, Xinzhuo, et al.
Publicado: (2014)

Calcium binding of the antifungal protein PAF: Structure, dynamics and function aspects by NMR and MD simulations
por: Fizil, Ádám, et al.
Publicado: (2018)

The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans
por: Binder, Ulrike, et al.
Publicado: (2010)

Antifungal Activity of an Original Amino-Isocyanonaphthalene (ICAN) Compound Family: Promising Broad Spectrum Antifungals
por: Nagy, Miklós, et al.
Publicado: (2020)

Preparation and Optical Study of 1-Formamido-5-Isocyanonaphthalene, the Hydrolysis Product of the Potent Antifungal 1,5-Diisocyanonaphthalene
por: Kopcsik, Erika, et al.
Publicado: (2023)

Membrane Sphingolipids Regulate the Fitness and Antifungal Protein Susceptibility of Neurospora crassa
por: Huber, Anna, et al.
Publicado: (2019)

Antibacterial and Antibiofilm Activities of Tryptoquivalines and Meroditerpenes Isolated from the Marine-Derived Fungi Neosartorya paulistensis, N. laciniosa, N. tsunodae, and the Soil Fungi N. fischeri and N. siamensis
por: Gomes, Nelson M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k6ap1cvh3gjiengi05o0l9t25k