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Time to Amyloid Positivity and Preclinical Changes in Brain Metabolism, Atrophy, and Cognition: Evidence for Emerging Amyloid Pathology in Alzheimer's Disease
Background: Aβ pathology is associated with longitudinal changes of brain metabolism, atrophy, and cognition, in cognitively healthy elders. However, Aβ information is usually measured cross-sectionally and dichotomized to classify subjects as Aβ-positive or Aβ-negative, making it difficult to evalu...
Autores principales: | Insel, Philip S., Ossenkoppele, Rik, Gessert, Devon, Jagust, William, Landau, Susan, Hansson, Oskar, Weiner, Michael W., Mattsson, Niklas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434146/ https://www.ncbi.nlm.nih.gov/pubmed/28567001 http://dx.doi.org/10.3389/fnins.2017.00281 |
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