Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A(4) analog: Protective mechanisms and long‐term effects on neurological recovery

BACKGROUND: Resolution of inflammation is an emerging new strategy to reduce damage following ischemic stroke. Lipoxin A(4) (LXA (4)) is an anti‐inflammatory, pro‐resolution lipid mediator that reduces neuroinflammation in stroke. Since LXA (4) is rapidly inactivated, potent analogs have been synthe...

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Detalles Bibliográficos
Autores principales: Hawkins, Kimberly E., DeMars, Kelly M., Alexander, Jon C., de Leon, Lauren G., Pacheco, Sean C., Graves, Christina, Yang, Changjun, McCrea, Austin O., Frankowski, Jan C., Garrett, Timothy J., Febo, Marcelo, Candelario‐Jalil, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434193/
https://www.ncbi.nlm.nih.gov/pubmed/28523230
http://dx.doi.org/10.1002/brb3.688

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