Why is Diagnosing MDD Challenging?

Depression is highly prevalent and one of the major contributors to disability worldwide. However, one of the findings from the DSM-5 field trials was that inter-rater reliability for diagnosing major depressive disorder was very poor. Why is diagnosing MDD so challenging? This article attempts to e...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai Municipal Bureau of Publishing 2016
Materias:
Forums
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434292/
https://www.ncbi.nlm.nih.gov/pubmed/28638210
http://dx.doi.org/10.11919/j.issn.1002-0829.216073
Descripción
Sumario:Depression is highly prevalent and one of the major contributors to disability worldwide. However, one of the findings from the DSM-5 field trials was that inter-rater reliability for diagnosing major depressive disorder was very poor. Why is diagnosing MDD so challenging? This article attempts to explain why undefined pathogenesis and complicated phenotypes complicate the diagnosis of MDD. However, further biomarker and translational research is still necessary to help clinicians screen and diagnose depression in the future rather than relying solely on current subjective diagnostic criteria.

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