Cargando…

Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon

Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could i...

Descripción completa

Detalles Bibliográficos
Autores principales: Cofre, Jaime, Abdelhay, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434308/
https://www.ncbi.nlm.nih.gov/pubmed/28553657
http://dx.doi.org/10.1155/2017/3578090
_version_ 1783237022999117824
author Cofre, Jaime
Abdelhay, Eliana
author_facet Cofre, Jaime
Abdelhay, Eliana
author_sort Cofre, Jaime
collection PubMed
description Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. Thus, this “cancer process” allows the harmonious and coherent construction of the embryo structural base, and its implementation as the embryonic process involves joint regulation of differentiation, proliferation, cell invasion, and migration, enabling the human being recreation of every generation. On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context.
format Online
Article
Text
id pubmed-5434308
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-54343082017-05-28 Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon Cofre, Jaime Abdelhay, Eliana ScientificWorldJournal Review Article Despite numerous advances in cell biology, genetics, and developmental biology, cancer origin has been attributed to genetic mechanisms primarily involving mutations. Embryologists have expressed timidly cancer embryological origin with little success in leveraging the discussion that cancer could involve a set of conventional cellular processes used to build the embryo during morphogenesis. Thus, this “cancer process” allows the harmonious and coherent construction of the embryo structural base, and its implementation as the embryonic process involves joint regulation of differentiation, proliferation, cell invasion, and migration, enabling the human being recreation of every generation. On the other hand, “cancer disease” is the representation of an abnormal state of the cell that might happen in the stem cells of an adult person, in which the mechanism for joint gene regulating of differentiation, proliferation, cell invasion, and migration could be reactivated in an entirely inappropriate context. Hindawi 2017 2017-05-03 /pmc/articles/PMC5434308/ /pubmed/28553657 http://dx.doi.org/10.1155/2017/3578090 Text en Copyright © 2017 Jaime Cofre and Eliana Abdelhay. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Cofre, Jaime
Abdelhay, Eliana
Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
title Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
title_full Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
title_fullStr Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
title_full_unstemmed Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
title_short Cancer Is to Embryology as Mutation Is to Genetics: Hypothesis of the Cancer as Embryological Phenomenon
title_sort cancer is to embryology as mutation is to genetics: hypothesis of the cancer as embryological phenomenon
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434308/
https://www.ncbi.nlm.nih.gov/pubmed/28553657
http://dx.doi.org/10.1155/2017/3578090
work_keys_str_mv AT cofrejaime canceristoembryologyasmutationistogeneticshypothesisofthecancerasembryologicalphenomenon
AT abdelhayeliana canceristoembryologyasmutationistogeneticshypothesisofthecancerasembryologicalphenomenon