A strategy to improve phasing of whole-genome sequenced individuals through integration of familial information from dense genotype panels

BACKGROUND: Haplotype reconstruction (phasing) is an essential step in many applications, including imputation and genomic selection. The best phasing methods rely on both familial and linkage disequilibrium (LD) information. With whole-genome sequence (WGS) data, relatively small samples of referen...

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Detalles Bibliográficos
Autores principales: Faux, Pierre, Druet, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434521/
https://www.ncbi.nlm.nih.gov/pubmed/28511677
http://dx.doi.org/10.1186/s12711-017-0321-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434521/
https://www.ncbi.nlm.nih.gov/pubmed/28511677
http://dx.doi.org/10.1186/s12711-017-0321-6

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