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Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies

BACKGROUND: Sarcopenia, an age-related decline in muscle mass and function, is one of the most important health problems in elderly with a high rate of adverse outcomes. However, several studies have investigated the prevalence of sarcopenia in the world, the results have been inconsistent. The curr...

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Autores principales: Shafiee, Gita, Keshtkar, Abbasali, Soltani, Akbar, Ahadi, Zeinab, Larijani, Bagher, Heshmat, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434551/
https://www.ncbi.nlm.nih.gov/pubmed/28523252
http://dx.doi.org/10.1186/s40200-017-0302-x
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author Shafiee, Gita
Keshtkar, Abbasali
Soltani, Akbar
Ahadi, Zeinab
Larijani, Bagher
Heshmat, Ramin
author_facet Shafiee, Gita
Keshtkar, Abbasali
Soltani, Akbar
Ahadi, Zeinab
Larijani, Bagher
Heshmat, Ramin
author_sort Shafiee, Gita
collection PubMed
description BACKGROUND: Sarcopenia, an age-related decline in muscle mass and function, is one of the most important health problems in elderly with a high rate of adverse outcomes. However, several studies have investigated the prevalence of sarcopenia in the world, the results have been inconsistent. The current systematic review and meta- analysis study was conducted to estimate the overall prevalence of sarcopenia in both genders in different regions of the world. METHODS: Electronic databases, including MEDLINE (via PubMed), SCOPUS and Web of Science were searched between January 2009 and December 2016. The population- based studies that reported the prevalence of sarcopenia in healthy adults aged ≥ 60 years using the European Working Group on Sarcopenia in Older People (EWGSOP), the International Working Group on Sarcopenia (IWGS) and Asian Working Group for Sarcopenia (AWGS) definitions, were selected. According to these consensual definitions, sarcopenia was defined by presence of low muscle mass (adjusted appendicular muscle mass for height) and muscle strength (handgrip strength) or physical performance (the usual gait speed). The random effect model was used for estimation the prevalence of sarcopenia. The sex-specific prevalence of sarcopenia and 95% confidence interval (CI) were calculated using the Binomial Exact Method. Heterogeneity was assessed by subgroup analysis. RESULTS: Thirty- five articles met our inclusion criteria, with a total of 58404 individuals. The overall estimates of prevalence was 10% (95% CI: 8-12%) in men and 10% (95% CI: 8-13%) in women, respectively. The prevalence was higher among non- Asian than Asian individuals in both genders especially, when the Bio-electrical Impedance Analysis (BIA) was used to measure muscle mass (19% vs 10% in men; 20% vs 11% in women). CONCLUSION: Despite the differences encountered between the studies, regarding diagnostic tools used to measure of muscle mass and different regions of the world for estimating parameters of sarcopenia, present systematic review revealed that a substantial proportion of the old people has sarcopenia, even in healthy populations. However, sarcopenia is as a consequence of the aging progress, early diagnosis can prevent some adverse outcomes.
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spelling pubmed-54345512017-05-18 Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies Shafiee, Gita Keshtkar, Abbasali Soltani, Akbar Ahadi, Zeinab Larijani, Bagher Heshmat, Ramin J Diabetes Metab Disord Research Article BACKGROUND: Sarcopenia, an age-related decline in muscle mass and function, is one of the most important health problems in elderly with a high rate of adverse outcomes. However, several studies have investigated the prevalence of sarcopenia in the world, the results have been inconsistent. The current systematic review and meta- analysis study was conducted to estimate the overall prevalence of sarcopenia in both genders in different regions of the world. METHODS: Electronic databases, including MEDLINE (via PubMed), SCOPUS and Web of Science were searched between January 2009 and December 2016. The population- based studies that reported the prevalence of sarcopenia in healthy adults aged ≥ 60 years using the European Working Group on Sarcopenia in Older People (EWGSOP), the International Working Group on Sarcopenia (IWGS) and Asian Working Group for Sarcopenia (AWGS) definitions, were selected. According to these consensual definitions, sarcopenia was defined by presence of low muscle mass (adjusted appendicular muscle mass for height) and muscle strength (handgrip strength) or physical performance (the usual gait speed). The random effect model was used for estimation the prevalence of sarcopenia. The sex-specific prevalence of sarcopenia and 95% confidence interval (CI) were calculated using the Binomial Exact Method. Heterogeneity was assessed by subgroup analysis. RESULTS: Thirty- five articles met our inclusion criteria, with a total of 58404 individuals. The overall estimates of prevalence was 10% (95% CI: 8-12%) in men and 10% (95% CI: 8-13%) in women, respectively. The prevalence was higher among non- Asian than Asian individuals in both genders especially, when the Bio-electrical Impedance Analysis (BIA) was used to measure muscle mass (19% vs 10% in men; 20% vs 11% in women). CONCLUSION: Despite the differences encountered between the studies, regarding diagnostic tools used to measure of muscle mass and different regions of the world for estimating parameters of sarcopenia, present systematic review revealed that a substantial proportion of the old people has sarcopenia, even in healthy populations. However, sarcopenia is as a consequence of the aging progress, early diagnosis can prevent some adverse outcomes. BioMed Central 2017-05-16 /pmc/articles/PMC5434551/ /pubmed/28523252 http://dx.doi.org/10.1186/s40200-017-0302-x Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Shafiee, Gita
Keshtkar, Abbasali
Soltani, Akbar
Ahadi, Zeinab
Larijani, Bagher
Heshmat, Ramin
Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
title Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
title_full Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
title_fullStr Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
title_full_unstemmed Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
title_short Prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
title_sort prevalence of sarcopenia in the world: a systematic review and meta- analysis of general population studies
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434551/
https://www.ncbi.nlm.nih.gov/pubmed/28523252
http://dx.doi.org/10.1186/s40200-017-0302-x
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